A 4-year-old with hemolytic uremic syndrome (HUS) has the following labs: Hemoglobin: 8.2 g/dL (Normal range: 11-14g/dL) Platelets 82,000/mm³ (Normal range: 150,000-400,000/mm³) Creatinine: 3.1 mg/dL (Normal range: 0.2-0.7 mg/dL) Which clinical manifestations are directly explained by the destruction of red blood cells and platelet consumption? Select all that apply.