This medication works in the high-ceiling loop diuretics work in the loop of Henle. It blocks the reabsorption of sodium and chloride and prevents the reabsorption of water, which causes extensive diuresis even with severe renal impairment

This medication works in the distal tubule to block the reabsorption of sodium and chloride and prevents the reabsorption of water.

This medication reduces intracranial pressure and intraocular pressure by raising serum osmolality and drawing fluid back into the vascular and extravascular space.

This medication blocks the action of aldosterone (sodium and water retention), which results in potassium retention and the excretion of sodium and water.