The client’s core body temperature reached the new thermoregulatory set point and the body is trying to prevent overheating

An exogenous pyrogen is directly resetting the client’s thermoregulatory set point in the anterior pituitary

The client is experiencing hyperthermia and the body’s mechanisms to control heat are no longer working effectively

An endogenous pyrogen is stimulating the production of leukotrienes to increase the thermoregulatory set point of the hypothalamus