The endocrine gland releases digestive enzymes directly into the duodenum, while the exocrine gland secretes hormones like insulin into the bloodstream.

Both endocrine and exocrine glands of the pancreas secrete hormones that regulate metabolism, but only the endocrine gland produces enzymes for digestion

Exocrine glands secrete hormones systemically to regulate blood glucose, whereas endocrine glands release digestive enzymes locally into the gastrointestinal tract.

The exocrine gland produces digestive enzymes into the duodenum, while the endocrine gland secretes hormones like insulin and glucagon directly into the bloodstream to regulate blood sugar levels.