You can take an additional dose of ibuprofen if the headache does not subside within 30 minutes.

You can safely combine ibuprofen with other NSAIDs or aspirin for more effective pain relief.

Take ibuprofen with food or milk to minimize gastrointestinal upset.

Acetaminophen does not increase bleeding time and has a low incidence of gastrointestinal (GI) adverse effects.

Do not exceed a total daily dose of 1.200 mg to avoid toxicity of acetaminophen,

Monitor for signs of gastrointestinal bleeding, such as black or tarry stools.