A. “The vaccination must be administered in two doses.”: This assumes a hepatitis C vaccine exists and has a two-dose schedule; no licensed hepatitis C vaccine exists to have any dosing schedule. B. “Have you received the hepatitis B vaccination?”: Hepatitis B does have a vaccine (so asking about it can be useful), but it does not answer the client’s request about hepatitis C. This response redirects rather than directly addressing the client’s statement. C. “There is no vaccination against hepatitis C.”: This directly and accurately answers the client’s statement by stating that no vaccine currently exists for hepatitis C. D. "Why are you interested in receiving this vaccine?": Acceptable as a follow-up question (explores risk/exposure), but it does not first correct the factual misunderstanding; best practice is to answer the factual question first, then explore motivations.