Choice C is correct. This is correct because rapid-acting insulin (lispro, aspart, glulisine) should be given within 10-15 minutes before a meal or while the client is actively eating.

Choices A, B, and D are incorrect. PPIs (omeprazole, pantoprazole) should not be given with a meal. The medication is intended to ameliorate esophageal reflux symptoms, and medications in this class are intended to be given 30 minutes before the main meal of the day. Glucocorticoids (prednisone) may cause GI irritation and cause ulcers. To minimize GI irritation, the client should take the medication with food and avoid concurrent use of NSAIDs. Finally, when a client is taking levodopa-carbidopa for Parkinson's disease, the client is instructed to take the medication one-half hour before eating a protein-containing meal or one hour after. Protein-dense meals given with the medication interfere with the medication's efficacy. The recommendation is for the client to eat higher protein–containing foods later in the day or small amounts over the course of the day.

✓ The three rapid-acting insulins are lispro, aspart, and glulisine.

✓ The client needs to take this insulin 10-15 minutes before a meal or while actively eating.

✓ A rapid-acting insulin is utilized as correctional insulin before meals to prevent post-prandial hyperglycemia.

✓ This type of insulin is commonly loaded into an insulin pump.