Choice A reason: Using the TPN line for all IV medications is unsafe because TPN solutions are highly concentrated and incompatible with many medications. Mixing drugs with TPN can cause precipitation, infection risk, or altered drug absorption. A dedicated line is required for TPN to maintain sterility and prevent complications. Choice B reason: An infusion pump is essential for TPN administration because it ensures precise control of the infusion rate. TPN contains concentrated glucose and electrolytes, and rapid infusion can cause dangerous metabolic shifts such as hyperglycemia or fluid overload. Pumps prevent accidental boluses and maintain steady delivery. Choice C reason: Monitoring daily weights is critical because TPN can rapidly alter fluid balance and nutritional status. Weight trends help detect fluid retention, dehydration, or inadequate nutrition. This allows the nurse to evaluate the effectiveness of therapy and adjust the plan of care accordingly. Choice D reason: Laboratory values must be monitored frequently because TPN affects electrolytes, glucose, liver function, and renal function. Abnormalities such as hypokalemia, hyperglycemia, or elevated liver enzymes can occur. Monitoring labs ensures early detection of complications and guides adjustments in the TPN formula. Choice E reason: Providing oral care if the patient is NPO is important because lack of oral intake increases the risk of mucosal dryness, infection, and discomfort. Oral care maintains hygiene, prevents bacterial overgrowth, and promotes patient comfort even when nutrition is delivered parenterally.