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    Dosage Calculations

    Critical Care and Titration Calculations

    Overview

    Critical care medications, such as vasopressors, are often ordered in micrograms per kilogram per minute (mcg/kg/min). These calculations are complex because they involve weight, time, and very small units of measurement. Nurses must be able to convert these orders into mL/hr to program infusion pumps accurately and adjust them based on real-time hemodynamic monitoring.

    Key nursing concepts

    • Conversion between milligrams and micrograms.
    • Incorporation of patient weight into the time-based calculation.
    • Calculation of the infusion rate in mL/hr from a mcg/kg/min order.
    • Understanding the therapeutic objectives of titration (e.g., maintaining MAP).
    • Calculation of the concentration of the drug in the IV bag.
    • Safety limits for maximum infusion rates of potent vasoactive drugs.

    Important nursing considerations

    • Monitor the patient's blood pressure and heart rate every 5 to 15 minutes.
    • Ensure the infusion is delivered through a central line if possible.
    • Verify the medication concentration (mg in mL) before starting the pump.
    • Use a microdrip or volumetric pump for precise delivery.
    • Titrate the medication slowly and strictly according to the provider's parameters.
    • Assess the IV site for extravasation, which can cause tissue necrosis.

    Patient teaching

    • Explain that the medication is helping to support heart and blood pressure.
    • Inform the patient that they will be monitored very closely with frequent checks.
    • Advise the patient to report any chest pain or headache immediately.
    • Explain the purpose of the various monitors and alarms in the room.

    Related practice questions

    Real questions from the NursGuru bank, each with the answer and rationale.

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    Critical Care and Titration Calculations flashcards

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