Dosage Calculations
Critical Care and Titration Calculations
Overview
Critical care medications, such as vasopressors, are often ordered in micrograms per kilogram per minute (mcg/kg/min). These calculations are complex because they involve weight, time, and very small units of measurement. Nurses must be able to convert these orders into mL/hr to program infusion pumps accurately and adjust them based on real-time hemodynamic monitoring.
Key nursing concepts
- Conversion between milligrams and micrograms.
- Incorporation of patient weight into the time-based calculation.
- Calculation of the infusion rate in mL/hr from a mcg/kg/min order.
- Understanding the therapeutic objectives of titration (e.g., maintaining MAP).
- Calculation of the concentration of the drug in the IV bag.
- Safety limits for maximum infusion rates of potent vasoactive drugs.
Important nursing considerations
- Monitor the patient's blood pressure and heart rate every 5 to 15 minutes.
- Ensure the infusion is delivered through a central line if possible.
- Verify the medication concentration (mg in mL) before starting the pump.
- Use a microdrip or volumetric pump for precise delivery.
- Titrate the medication slowly and strictly according to the provider's parameters.
- Assess the IV site for extravasation, which can cause tissue necrosis.
Patient teaching
- Explain that the medication is helping to support heart and blood pressure.
- Inform the patient that they will be monitored very closely with frequent checks.
- Advise the patient to report any chest pain or headache immediately.
- Explain the purpose of the various monitors and alarms in the room.
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